Bone Regeneration

Our research is focused at the intersection of materials science and human biology to develop a range of biomaterials that promote healing and aid the body`s natural tissue repair mechanisms, and to understand how chemistry, topography and architecture of biomaterials can act as niche to trigger a specific cellular function, particularly in musculoskeletal system( Bone, cartilage, osteochondral tissue, tendon, skin and entheses). We integrate traditional and advance techniques to fabricate the biomaterials with similar the physical, mechanical and chemical properties to the target tissue to permanently replace or regenerate the damaged tissue and restore the function.  

Current projects

  • New technique to immobilize bioactive molecules to the surface of ceramic scaffolds to ensure spatiotemporal release of bone morphogenetic protein-2 for treatment of large bone defects.

      (In collaboration with department of Experimental Trauma Surgery at the Technical University Munich).

Bone 1

  Bone2

 

  •  Utilising 3D printing technique and computational modelling to fabricate modular load bearing composite system for spinal fusion.

  Bone 3  

  • Osteogenic and angiogenic properties of synthetic, porous and ion doped bone precursor mimicked nanoparticles in interaction with mesenchymal stem cells and endothelial cells.

Bone5

 

bone 4                                                                                                                                                                                                                                           

  •  3D printing of bioceramics bone substitutes at room temperature.

 Bone 6

  •  Influence of imprinted physical cues on surface of biceramics on modulating function of bone forming cells.

biceramics

Bone8

biceramics1

 

biceramics